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Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1a expression

Paper written by Joseph Willson (OPTIMA 2014) and Professor Sarah Walmsley (open access). Link to original paper here: Willson et al (2016)

Raman spectroscopy and regenerative medicine: a review

Review article written by Katie Ember (OPTIMA 2015), Professor Karen Faulds, Professor Stuart Forbes and Dr Colin Campbell (open access). Link to original paper: Ember et al (2017)

Tricarbocyanine N-triazoles: the scaffold-of-choice for long-term near-infrared imaging of immune cells in vivo

Paper written by Jamie Scott (OPTIMA 2016) and Professor Marc Vendrell (open access). Link to original article: Scott, Vendrell et al (2018)

Augmentation of human monocyte responses to lipopolysaccharide by the protein S and Mer/Tyro3 receptor tyrosine kinase axis

Paper written by Nicole Barth, Professor Adriano Rossi and Professor Ian Dransfield (paywall). Link to original article: Barth, Rossi and Dransfield (2018)

Science education adaptations for non-textbook instruction to students with learning and other disabilities: a chronological literature review

Review article written by Maria Panagopoulou (OPTIMA 2016) et al. Link to original article: Panagopoulou et al 2018

Towards automated cancer screening: Label‐free classification of fixed cell samples using wavelength modulated Raman spectroscopy

Paper written by Lana Woolford (OPTIMA 2015) and Professor Simon Herrington (open access). Link to original paper: Woolford et al 2018

Extracellular vesicles arising from apoptotic cells in tumors: roles in cancer pathogenesis and potential clinical applications

Paper written by Catherine Lynch (OPTIMA 2014), Maria Panagopoulou (OPTIMA 2016) and Professor Chris Gregory (open access). Link to original article: Lynch, Panagopoulou and Gregory 2017

Scottish pilot of The Brilliant Club

The Brilliant Club is an award-winning charity that exists to increase the number of pupils from under-represented background progressing to highly-selective universities. They do this by mobilizing the PhD community to share its academic expertise with state schools. Helen Parker and Adeel Shafi were chosen to be the first PhD researchers to pilot The Brilliant Club in Scotland, at Holyrood and Hyndland Secondary Schools.

Build your own spectrophotometer

"Build Your Own Spectrometer" is a hands-on course in which groups of students are given the necessary components to build a spectrometer. The course teaches, through a variety of lectures, workshops and

independent study exercises, how to assemble a fully functional spectrometer. It gives a unique insight into how an optical spectrometer works as well as how to design, build and optimise optical spectroscopy systems. This course not only provides bespoke training in the fundamental workings of a spectrometer and allow students to build their own working system, it also develops their skills in entrepreneurship and marketing as they have to find the place for their spectrometer within the current and future technology market as well as satisfy the ‘customer’ requirements.

IP generation from Grand Challenge

Paul Cowling, Dawn Gillies and Clara Vergez developed a novel idea during their first year Grand Challenge course. It has subsequently seeded a Masters project and PhD between Engineering and Medicine to follow up on the concept.